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Group B Streptococcus Informed Consent/Refusal
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What is it? Group B
Streptococcus (GBS) is a bacterium that can be carried in the genital,
urinary, digestive, and respiratory tracts. Up to one third of all
adults carry GBS in their intestines, and one in four women carry it in
their vaginas. Frequently, those who are carriers are asymptomatic
(without symptoms) so often they do not realize that they are colonized.
However, during pregnancy, birth and the postpartum period, GBS can
cause serious problems for both mom and baby. What effect
does it have? Prenatally,
women with GBS have a higher incidence of urinary tract infections,
premature rupture of the amniotic membrane (bag of water) and
chorioamnionitis (infection of the amniotic membrane). Although urinary
tract infections can be treated with antibiotics or alternative
therapies, infection or rupture of the amniotic sack can cause premature
birth or even fetal death. Although the
overall GBS neonatal infection rate is only 0.18% (1.8/1000 live
births), GBS is the most common cause of sepsis (blood infection),
pneumonia and meningitis (infection of the fluid and lining surrounding
the brain and central nervous system) in the newborn. The rate of
infection increases to 0.5% (5/1000 live births) for babies born to
mothers who are known to be colonized with GBS but who are without
symptoms, and up to 4% (40/1000) for babies born to mothers who are
colonized and have symptoms. Most cases of
neonatal GBS infections (75%) occur during the first week of life
(early-onset), and most of these are apparent a few hours after birth.
These occurrences can be directly attributed to exposure of the baby
during birth to GBS colonization in the mother. The remaining 25%
develop after the first week of life (late-onset), and frequently cause
meningitis. Only about half of the late-onset infections can be
attributed to exposure to colonization of the mother, leaving the source
of the other half unknown. The mortality (death) rate for the infected
newborns is 5-20%, and babies that survive, particularly those with
meningitis, may have long-term problems such as hearing or vision loss
or learning disabilities. Postpartum,
women with GBS have a higher incidence of endometritis (infection of the
uterine lining) and puerperal sepsis (blood infection related to the
birth). How do I
know if I have it? Testing
policies vary, but if you have had a urinary tract infection caused by
GBS, or if you have ever delivered a GBS-positive baby, you are
considered to be positive for GBS. Otherwise, GBS colonization can be
detected during pregnancy by a culture grown from a vaginal/rectal swab.
To most accurately predict a woman’s GBS status for delivery, the
Centers for Disease Control recommend that the swab be taken between the
35th and 37th week of pregnancy. Being positive
means you are colonized with GBS and at risk of transmitting the disease
to your newborn, particularly if you have a fever during labor, if your
membranes are ruptured for more than 18 hours before delivery, or if you
have preterm (before 37 weeks) labor or rupture of membranes. What can I
do if I have it? Some care
providers prescribe oral antibiotics for women with positive cultures,
but studies show that prenatal oral antibiotics do not reliably prevent
re-colonization of the mother once the treatment is finished, and
therefore do not protect the newborn from GBS exposure. The
administration of intravenous (or intramuscular injection) antibiotics
such as Ampicillin, Amoxicillin or Erythromycin during labor has been
found to be more effective (although not 100% effective) in preventing
newborn GBS. However,
antibiotics also may pose a threat to mother or baby, and some reactions
may be life threatening. Therefore, any decision to take antibiotics
should include consideration of the risk factors associated with
antibiotics, especially since women who are colonized with GBS but do
not develop any symptoms are at a relatively low risk (0.5%) of
delivering a baby with GBS disease, Statistically, 10% (100/1000) of
people who receive antibiotics experience a mild allergic reaction (such
as a rash), 0.01% (1/10,000) experience a mild anaphylactic reaction,
and 0.001% (1/100,000) experience a severe anaphylactic reaction
resulting in death. Although it is uncommon, an unborn baby can
experience a severe reaction even if the mother’s reaction is not life
threatening. What other
options do I have? Experiential
data has shown several alternative treatments to be effective in
combating GBS colonization thereby minimizing infant exposure. These
include an oral garlic/echinacea herbal regimen, intra-vaginal use of
garlic oil capsules, tea tree vaginal suppositories, and homeopathic
treatment. However, because these are non-medical treatments, there is
no statistical data to support their effectiveness.
In addition,
there is a new protocol being tested that calls for the use of
chlorohexidine (Hibicleanse) as a vaginal lubricant during labor. This
surgical wash has proven effective against streptococcal bacteria in
dental use, and has been used as a bactericide in obstetrics and surgery
for many years. Some individuals experience a mild allergic reaction to
chlorohexidine, usually in the form of a mild rash, but severe reactions
are extremely rare, and no adverse effects to the newborn have been
noted. |